The previous 47 meetings to be held in the second city have been evenly matched, Blues winning 19 times to Forest's 18. The hosts won last season's corresponding fixture 2-1 in February.
Lee Clark's side are unbeaten in six but the Birmingham manager will rotate his resources over the busy festive period.
He told the Birmingham Mail: “What I have learned is that over the short period of time, you can’t go into each game with the same personnel, no matter what the result."