Forest head into the game having stopped their run of poor form with the 1-0 win over Derby County before the international break, a result that has stopped talk of Dougie Freedman being under pressure dead in its tracks for the moment.
The template for that victory, with the Reds maintaining their formation, defending strongly and attacking on the counter, is unlikely to change at Griffin Park with the first goal again set to be crucial as it has been in the last two away games at Sheffield Wednesday and Preston North End.
Brentford remain in a slightly unusual situation on the managerial front as Lee Carsley remains in temporary charge but has consistently stated he does not want the job on a permanent basis despite an upturn in results since he replaced Marinus Dijkhuizen.
While Freedman will hope to have some of his injured players back for the game, Brentford will be without Marco Djuricin for up to two months.
The frontman, on loan at Brentford from Red Bull Salzburg, suffered ankle ligament damage at Blackburn before the international break.
22-year-old Djuricin has scored four goals to date for the Bees including a well-received winner in the recent London derby against Queens Park Rangers.
Brentford's goal threat will surely come from Alan Judge and Lasse Vibe who have 11 between them in the Championship this season.
Denmark international Vibe arrived in the summer from IFK Goteborg.