A win over Cheltenham will send them up and manager Sean O'Driscoll said: "It is in our hands now and that is all you can ask.
"If we perform like we can do at Cheltenham, it will not matter what happens anywhere else."
Carlisle are the outsiders of three to take second place after their surprise defeat at Millwall.
"There's a shortage of energy you need at this stage and a few are running on empty," boss John Ward told BBC Radio Cumbria.
"It's not effort or fitness, but we just don't have that zip about us."