The game pits an Owls side top near the top of the form table with four wins and two draws from their last six matches against a Reds outfit towards the foot with three draws and three defeats from theirs.
Add to that the feel good factor generated by Sheffield Wednesday's 3-0 victory over Arsenal in the League Cup and the loan signing of striker Gary Hooper and 11/10 against a home victory looks attractive.
The glimmer of hope for Nottingham Forest supporters making the short journey up the M1 is the form they will have seen on previous away travels this season where Dougie Freedman's side have always been hard to break down even in the games they have lost.
Forest's six games on the road this season have yielded 2 wins, 2 draws and 2 defeats with 5 goals scored and 6 against.
A brace of early goals from Aaron Wilbraham sunk the Reds at Bristol City last time out but prior to that they had not conceded in the first-half away from home so if they are going to lose it may be close with Wednesday priced at 13/5 to win by a single goal.
Odds from Bet365